Computational Genomics, Medicine Genomics, System Biology

Personal genomes

Advances in genome science and technology offer a deeper understanding of biology while at the same time improving the practice of medicine. Genomics information could tell  us more story on our health.In 2008, Nature offered a special focus on “Personal Genomics” to focus on the on how genomes information help us known our health. As the price of sequencing is deducing, someday can say that my gene, my health. Here is a snapshot from Nature.

My genome. So what? Free access

Research is needed into the way individuals use their genomic information, and into protection from its abuse by others.

Nature 456, 1 (6 November 2008) doi:10.1038/456001a

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NEWS

How to get the most from a gene test

New tools squeeze more research out of personal genomics.
Erika Check Hayden

Nature 456, 11 (6 November 2008) doi:10.1038/456011a

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NEWS

Genomics takes hold in Asia

Collaborations among Asian scientists are just not as strong as those they share with scientists in the West. Why?
David Cyranoski

Nature 456, 12 (6 November 2008) doi:10.1038/456012a

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NEWS

Human genes are multitaskers

Up to 94% of human genes can generate different products
Heidi Ledford

NatureNews Published online 2 November 2008 doi:10.1038/news.2008.1199

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NEWS FEATURE

Personal genomes: The case of the missing heritability Free access

When scientists opened up the human genome, they expected to find the genetic components of common traits and diseases. But they were nowhere to be seen. Brendan Maher shines a light on six places where the missing loot could be stashed away.
Brendan Maher

Nature 456, 18–21 (6 November 2008) doi:10.1038/456018a

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NEWS FEATURE

DNA sequencing: Standard and pores

Could the next generation of genetic sequencing machines be built from a collection of minuscule holes? Katharine Sanderson reports.
Katharine Sanderson

Nature 456, 23–25 (6 November 2008) doi:10.1038/456023a

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NEWS FEATURE

Personal genomes: A disruptive personality, disrupted Free access

Eric Schadt revels in making people uncomfortable with his science. Bryn Nelson reports how the bioinformatics rabble-rouser hopes to charge ahead in the face of his company’s disintegration.
Bryn Nelson

Nature 456, 26–28 (6 November 2008) doi:10.1038/456026a

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COMMENTARY

When consent gets in the way Free access

As the prospect of personal genomes for all promises to make personal health records a reality, mandating consent does not protect privacy or ensure public benefit.
Patrick Taylor

Nature 456, 32 (6 November 2008) doi:10.1038/456032a

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COMMENTARY

Misdirected precaution Free access

Personal-genome tests are blurring the boundary between experts and lay people. It’s time rethink outdated models of regulation.
Barbara Prainsack, Jenny Reardon, Richard Hindmarsh, Herbert Gottweis, Ursula Naue & Jeantine E. Lunshof

Nature 456, 34 (6 November 2008) doi:10.1038/456034a

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