A Free Online Book on Human Genome

Recently, I just read a online book on Human Genome. Its an well write book, thanks the author for share. Enjoy the Book:

Human Molecular Genetics, 2nd edition

Tom Strachan1 and Andrew P Read2
1University of Newcastle, Newcastle-upon-Tyne, UK
2University of Manchester, Manchester, UK
New York: Wiley-Liss; 1999.
ISBN: 1-85996-202-5
Excerpt

The idea for this book grew from two earlier efforts, The Human Genome (TS; BIOS Scientific Publishers, 1992) and Medical Genetics, an Illustrated Outline (APR; Gower Medical Publishing, 1989). In these small books we tried to develop a treatment of human genetics based on understanding the structure and function of the normal human genome. Traditionally, textbooks of human genetics tended to start by considering meiosis and the way diseases segregate in pedigrees, whilst textbooks of molecular genetics rarely emphasized human topics. Until recently this was inevitable because so little was understood about the normal human genome. The Human Genome Project has changed all that, and the present book is an attempt to provide a comprehensive integrated study of human molecular genetics.

Table of Contents

SVMs in computational Biology

Support vector machines (SVMs) are a set of supervised learning methods, they could used in statistical patterns classification and recognize.  As its easy extension and  could be deal the high dimension data, its could be used widely in computational biology. Here are two paper published in Education issue of  Plos Computational, which introduced Machine Learning and SVMs to Computational Biology:

1. Support Vector Machines and Kernels for Computational Biology

Asa Ben-Hur1#, Cheng Soon Ong2,3#¤, Sören Sonnenburg4, Bernhard Schölkopf3, Gunnar Rätsch2*

1 Department of Computer Science, Colorado State University, Fort Collins, Colorado, United States of America, 2 Friedrich Miescher Laboratory, Max Planck Society, Tübingen, Germany, 3 Max Planck Institute for Biological Cybernetics, Tübingen, Germany, 4 Fraunhofer Institute FIRST, Berlin, Germany

Introduction

The increasing wealth of biological data coming from a large variety of platforms and the continued development of new high-throughput methods for probing biological systems require increasingly more sophisticated computational approaches. Putting all these data in simple-to-use databases is a first step; but realizing the full potential of the data requires algorithms that automatically extract regularities from the data, which can then lead to biological insight.

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Personal genomes

Advances in genome science and technology offer a deeper understanding of biology while at the same time improving the practice of medicine. Genomics information could tell  us more story on our health.In 2008, Nature offered a special focus on “Personal Genomics” to focus on the on how genomes information help us known our health. As the price of sequencing is deducing, someday can say that my gene, my health. Here is a snapshot from Nature.

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