COSINE: A Web Server for Clonal and Subclonal Structure Inferencing and Evolution in Cancer Genomics. COSINE is freely accessible at http://www.clab-cosine.net or http://bio.rj.run:48996/cun-web/.
我们在COSINE中对12种subclonal推断算法实现了界面化，用户可直接登录网址计算。欢迎测试和反馈使用体验。COSINE中的12种方法是：
- 1.Sclust : Software: rj.run/downloads/Sclust.tgz
- 2.Pyclone: https://shahlab.ca/projects/pyclone/
- 3.FastClone, https://github.com/GuanLab/FastClone_Guanlab
- 4.Dpclust, Software:https://github.com/Wedge-Oxford/dpclust
- 5.PhyloWGS: Software: https://github.com/morrislab/phylowgs
- 6.SciClone, Software: https://github.com/genome/sciclone
- 7.Svclone, Software: https://github.com/mcmero/Svclone
- 8.CLiP, Software:https://github.com/wwylab/CliP
- 9.TrAp: https://tinyheero.github.io/2015/08/26/TrAp.html
- 10.CITUP：http://sourceforge.net/projects/citup/
- 11.CloneFinder: https://github.com/gstecher/CloneFinderAPI
- 12.PhylogicNDThttps://github.com/broadinstitute/PhylogicNDT
Computational Genomics & Medicine 